"Lasciate ogne speranza, voi ch'intrate" (Abandon all hope, ye who enter here.) The words Dante places over the gates of hell are terrifying. And to turn that cause and effect around is to remind ourselves of the devastation wrought in lives where hope has gone.
Few people can have a more difficult start in life than those who were taken into care as children. Removed from their families, they may at a very young age have experienced terrible sadness and distress.