The Vatican's official daily has criticised global powers presently preparing for direct military action against Syria.
"The tones are becoming ever more drastic and the action being taken by the United Nations appears subjected to a sort of crossfire," the newspaper said.
"Various international actors appear no longer to consider the investigation a determining factor," it said, referencing the ongoing United Nations investigation into the alleged chemical weapons attack near Damascus on Wednesday 21 August.
It added that "what commitment there was" to a negotiated settlement "appears to be dying out".
That comment came before the UK parliament voted against a government proposal to agree "in principle" to a military strike on Syria, but relates directly to the US administration's latest threats of a 'go it alone' strategy as scepticism about escalation increases.
Pope Francis has called also for an end to the fighting in Syria, and for moves towards diplomatic and political rather than military solutions in the region.
The Vatican has always opposed the rush to armed intervention, pointing to the havoc and death caused by the US-led war to topple Saddam Hussein in Iraq in 2003.
* More on Syria from Ekklesia: http://www.ekklesia.co.uk/syria